Hereditary Angioedema
HAE
Hereditary angioedema is a rare genetic disorder that causes sudden, recurring episodes of swelling in the skin, throat, or digestive tract. It is caused by a deficiency or dysfunction of C1 esterase inhibitor, leading to increased levels of bradykinin, a chemical that makes blood vessels leak fluid into surrounding tissues. The swelling often affects the face, hands, feet, airway, or abdomen, and may cause severe abdominal pain or life-threatening airway obstruction. Unlike allergic angioedema, HAE does not cause itching or hives and does not respond to antihistamines or steroids. Treatment involves C1-INH replacement or bradykinin-blocking medications to prevent or stop attacks.
AI Summary of Treatment Experiences
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Hereditary angioedema is a rare genetic disorder that causes sudden, recurring episodes of swelling in the skin, throat, or digestive tract. It is caused by a deficiency or dysfunction of C1 esterase inhibitor, leading to increased levels of bradykinin, a chemical that makes blood vessels leak fluid into surrounding tissues. The swelling often affects the face, hands, feet, airway, or…
Treatments Shared by the Community
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10 Treatments for Hereditary Angioedema
C1 esterase inhibitor (human)
C1 esterase inhibitor (human)
C1 esterase inhibitor (recombinant)
Firazyr
Kalbitor
Takhzyro
Orladeyo
Odzorna
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