Ibuprofen is an over-the-counter NSAID that may help reduce inflammation and pain from foraminal stenosis, especially when nerve irritation causes back, neck, arm, or leg pain. It can be useful for short-term flare-ups, but it does not reverse the narrowing of the foramen or fix the underlying structural problem. Benefits may include less pain, improved mobility, and reduced need for stronger medications. Side effects can include stomach irritation, bleeding risk, kidney issues, increased blood pressure, and interactions with blood thinners or other medications. It is usually best used at the lowest effective dose for the shortest necessary time, especially in older adults or people with kidney, stomach, heart, or bleeding problems.