Addyi (flibanserin) is a medication used to treat low sexual desire (hypoactive sexual desire disorder) in women, though it is primarily approved for premenopausal women. It works by affecting brain neurotransmitters such as serotonin, dopamine, and norepinephrine, which are involved in sexual desire. Some clinicians may consider it in select patients with decreased libido around menopause, but its use in postmenopausal women is less well established. The medication is taken once daily at bedtime and may take several weeks to show benefit. Side effects can include dizziness, fatigue, low blood pressure, and interactions with alcohol or certain medications, so careful use is important.