Lynkeduet is a newer medication designed to reduce moderate to severe vasomotor symptoms of menopause such as hot flashes and night sweats. It works by blocking neurokinin-3 receptors in the brain’s thermoregulation center, which helps calm the temperature misfires triggered by low estrogen levels. Unlike hormone replacement therapy, Lynkeduet is non-hormonal, making it an option for individuals who cannot or prefer not to use estrogen. It is typically taken once daily and may begin improving symptoms within weeks. Common side effects can include headaches, stomach upset, or sleep changes, and liver monitoring is recommended while on treatment.