Allergy & Immune

Fibromyalgia

Fibromyalgia is a chronic disorder characterized by widespread musculoskeletal pain, fatigue, and tenderness in specific areas of the body. It often coexists with symptoms such as sleep disturbances, cognitive difficulties (“fibro fog”), and mood disorders like anxiety or depression. The exact cause is unknown, but it is thought to involve abnormal pain processing in the central nervous system. Diagnosis is clinical, based on symptoms and the exclusion of other conditions. While there is no cure, treatment includes a combination of medications, physical activity, stress reduction, and cognitive behavioral therapy.

AI Summary of Treatment Experiences

Not medical advice.

Treatment for fibromyalgia involves a multi-modal approach, combining pharmacologic and non-pharmacologic interventions. First-line medications include SNRIs like duloxetine and milnacipran, as well as the gabapentinoid pregabalin, which help reduce pain, fatigue, and improve sleep. Cyclobenzaprine may be used off-label for nighttime symptom relief. Non-drug therapies such as cognitive behavioral therapy and regular aerobic exercise have strong evidence supporting their efficacy in improving quality of life, physical function, and mood in fibromyalgia patients.

Fibromyalgia

Treatments Shared by the Community

Explore what patients, caregivers, and clinicians have said about these treatments.

7 Treatments for Fibromyalgia

Prescription Medication
Milnacipran

Savella

5.0 (1)
Prescription Medication
Pregalbin

Lyrica

5.0 (1)
Prescription Medication
5.0 (1)
Mental Health
Prescription Medication
Cyclobenzaprine

Flexeril

4.0 (1)
Lifestyle
Prescription Medication
Naltrexone

Low dose naltrexone, LDN

(0)

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Choose treatments from the menu above to see how they compare side by side.

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