Fexofenadine

Other names: Allegra

Categories: Over the Counter Medication

Description:

Allegra (fexofenadine) is a second-generation antihistamine that helps relieve itching (pruritus) associated with eczema, though it does not treat the inflammation or skin barrier issues directly. It's often used as an adjunct therapy alongside moisturizers and topical steroids to help reduce scratching and improve comfort. Unlike older antihistamines,

Allegra is non-sedating, making it a good option for daytime use. Studies have shown it can reduce itch severity within 24 hours, helping to interrupt the itch-scratch cycle. It should be taken with water, as fruit juices like orange or grapefruit can interfere with its absorption.

Treatment For:

Eczema

AI generated Summary: Based on the author's review, Fexofenadine (Allegra) is an effective over-the-counter antihistamine that can help relieve itching associated with eczema, especially when allergies are involved. While it doesn't directly treat the underlying inflammation, studies suggest that combining fexofenadine with topical corticosteroids can significantly reduce itching in patients with atopic dermatitis. The author rates the treatment highly with a score of 5.

Reviews

Average rating: 5/5

Physician ( 1 )

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Average rating: 5.00/5

Total Reviews: 1

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All Physician Healthcare provider (non-physician) Healthcare Consumer (Patients & Caregivers)

Dr. Curbside

May 25, 2025

5.0

Allegra (fexofenadine) is an over-the-counter, non-drowsy antihistamine that can help relieve itching associated with eczema, particularly when allergies are a contributing factor. While it doesn't address the underlying inflammation of eczema, studies have shown that adding fexofenadine to topical corticosteroids can significantly reduce pruritus in atopic dermatitis patients . Allegra is generally well-tolerated, but it's important to take it with water, as fruit juices can decrease its absorption.

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