Tapinarof cream 1% is a prescription, non-steroidal topical treatment approved for mild to moderate eczema (atopic dermatitis) in patients as young as 2 years old. It works by activating the aryl hydrocarbon receptor (AhR), helping to reduce inflammation, strengthen the skin barrier, and relieve itching. Clinical trials showed significant improvements in skin clearance and itch reduction within 8 weeks. Unlike steroids, Vtama can be used on sensitive areas like the face, neck, and folds, and has no restrictions on duration or body surface area. Common side effects include mild folliculitis, headaches, and upper respiratory infections. It’s a promising steroid-free option for patients seeking long-term eczema control without the risks of skin thinning.