Categories: Prescription Medication
Description:
Theophylline is an off-label treatment for central sleep apnea that works by stimulating the brain’s respiratory centers and increasing diaphragmatic activity. It may be helpful in patients with CSA related to heart failure or neuromuscular conditions, especially when standard therapies like CPAP or ASV are not tolerated. However, its use is limited by a narrow therapeutic window and potential side effects such as insomnia, tremors, and cardiac arrhythmias. Because of these risks, theophylline is generally reserved as an adjunct therapy rather than first-line treatment. It requires careful monitoring and is less commonly used today due to the availability of safer, more effective alternatives.
Treatment For:
AI generated Summary: Based on the single review provided, Theophylline appears to have some efficacy in treating central sleep apnea, especially in patients with heart failure, by stimulating respiratory drive and reducing central events. However, its use is limited due to potential side effects and a narrow therapeutic range, making it more suitable as an adjunctive therapy or when other treatments are not appropriate.
Theophylline is an off-label treatment for central sleep apnea that stimulates respiratory drive and may reduce central events, particularly in heart failure patients. Due to its side effects and narrow therapeutic range, it is typically considered only as an adjunct or when other therapies are not suitable.
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