Subcutaneous apomorphine (Apokyn®) is a fast-acting dopamine agonist used as a rescue treatment for sudden “off” episodes in Parkinson’s disease. It is injected under the skin and can improve movement within minutes, though the benefit is short-lived. This makes it useful in advanced disease when standard medications wear off unpredictably. Side effects may include nausea, vomiting, low blood pressure, sleepiness, and injection site reactions, so patients often start with an anti-nausea medication. While not used as a daily maintenance drug, it provides an important option for quick symptom relief.