A sphenopalatine ganglion (SPG) block is a non-invasive or minimally invasive procedure used for acute migraine treatment, particularly in patients with severe or refractory headaches. It involves delivering a local anesthetic (usually lidocaine) to the SPG, a nerve cluster located deep in the nasal cavity, using a cotton swab, catheter, or spray. The block works by interrupting pain and autonomic pathways involved in migraine attacks. Relief is often rapid, sometimes within minutes, and the procedure is generally well tolerated. SPG blocks are increasingly used in emergency and outpatient settings as a non-systemic alternative to medications.