Semaglutide is a medicine that was first made to help people with diabetes, but doctors also use it to help people lose weight. It works by acting like a natural hormone in your body called GLP-1, which helps control hunger and blood sugar. Semaglutide makes you feel full faster and less hungry, so you eat less food. For weight loss, it’s sold under the name Wegovy and is given as a small shot once a week. Most people start with a low dose and slowly increase it to a higher dose, up to 2.4 milligrams each week. When used with healthy eating and exercise, it can help people lose about 15% of their body weight over time.