Roflumilast

Other names: Daliresp

Categories: Prescription Medication

Description:

Roflumilast (brand name Daliresp) is an oral phosphodiesterase-4 (PDE4) inhibitor used to reduce the risk of COPD exacerbations in patients with severe COPD and chronic bronchitis who have frequent flare-ups. It works by decreasing airway inflammation, complementing bronchodilator therapy. Roflumilast is not a bronchodilator itself and is typically used as an add-on to inhaled treatments like LABA or LAMA. Common side effects include weight loss, diarrhea, nausea, and insomnia, and it may not be well-tolerated by all patients. It's best suited for patients with ongoing exacerbations despite optimized inhaler use.

Treatment For:

Chronic Obstructive Pulmonary Disease

AI generated Summary: Based on the single review provided, Roflumilast is an oral anti-inflammatory medication used to reduce flare-ups in patients with severe COPD and chronic bronchitis who continue to have frequent exacerbations despite optimal inhaler therapy. However, due to potential side effects like weight loss and gastrointestinal symptoms, it is best suited for select patients who can tolerate it.

Reviews

Average rating: 3/5

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Average rating: 3.00/5

Total Reviews: 1

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All Physician Healthcare provider (non-physician) Healthcare Consumer (Patients & Caregivers)

ER9560

May 25, 2025

3.0

Roflumilast is typically used in patients with severe COPD and chronic bronchitis who continue to have frequent exacerbations despite optimal inhaler therapy. It’s an oral anti-inflammatory medication added to reduce flare-ups, especially when inflammation plays a major role. Due to potential side effects like weight loss and GI symptoms, it’s best suited for select patients who can tolerate it.

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