Prochlorperazine

Alternative Names: Compazine

Compazine (prochlorperazine) is an antiemetic that can be used to treat nausea and vomiting from gastroenteritis, though it is not a first-line option. It works by blocking dopamine receptors in the brain’s vomiting center. While it may provide symptom relief, it is less well studied for gastroenteritis compared to ondansetron and can cause side effects such as drowsiness, dizziness, or movement-related problems (extrapyramidal symptoms). Because of these risks, it is generally reserved for adults when other safer agents, like ondansetron, are unavailable or not effective.

Treatment Type: Prescription Medication

Treatment Class: Dopamine agonist

Treatment Modality: Genitorectal, Injection, Intravenous (IV), Oral

Prochlorperazine

Review Summary

4.0

1 Reviews

Preferred by 1 Reviewers

Based on the review, Prochlorperazine appears to be a secondary treatment for managing nausea and vomiting in gastroenteritis, particularly when first-line treatments like ondansetron are not suitable. While it can help alleviate symptoms, patients should be aware of potential side effects such as drowsiness and movement-related issues.

This summary was generated by users' reviews

Breakdown by Category

Each categories are rated on a 1–5 scale, with 5 being the most favorable outcome and 1 being the least. These scores are averaged across all user reviews to provide a clear sense of how this treatment typically performs in each area.

Cost
5.0
1 = Very Expensive 5 = Very Affordable

5.0

Very Affordable
Relief Speed
5.0
1 = No Relief 5 = Immediate Relief

5.0

Immediate Relief
Side Effects
4.0
1 = Intolerable Effect 5 = No Effect

4.0

Mild Effect
Treatment Line
3.0
1 = Third-line or more 5 = First-line

3.0

Second Line

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4.0

1 Reviews
5
0%
4
100%
3
0%
2
0%
1
0%

AI Summary of User Experiences

Not medical advice.

Based on the review, Prochlorperazine appears to be a secondary treatment for managing nausea and vomiting in gastroenteritis, particularly when first-line treatments like ondansetron are not suitable. While it can help alleviate symptoms, patients should be aware of potential side effects such as drowsiness and movement-related issues.

Reviews

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Cost
Very Expensive
$1000+
Expensive
$501 to $1000
Moderate Cost
$101 to $500
Affordable
$25 to $100
Very Affordable
$25
Relief Speed
No Relief
No noticeable improvement
Slow Relief
Several days to weeks
Moderate Relief
Within 1 - 3 days
Fast Relief
Within hours
Immediate Relief
Within minutes
Side Effect
Intolerable Side Effect
Caused treatment to stop or required hospitalization
Severe Side Effect
Difficult to tolerate, may require intervention
Moderate Side Effect
Noticeable, but manageable
Mild Side Effect
Minor, not bothersome
No Side Effect
Without any adverse effects
Treatment Line
Third-line or more
Used after second-line failed or multiple prior treatment
Second-line
Used after first-line treatment failed or was unsuitable
First-line
First treatment tried
Dr. Curbside

Dr. Curbside

Verified
Physician • Emergency Medicine • How doctors think about decisions — and what real-world experiences add
1 month ago
Prochlorperazine is a backup option for treating nausea and vomiting in gastroenteritis when ondansetron (Zofran) is not effective or available. It can help with symptoms but carries a higher risk of side effects like drowsiness or movement-related problems.
#VeryAffordable #ImmediateRelief #MildEffect #Second-line #Rescue/EmergencyUse
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