Ondansetron

Alternative Names: Zofran

Ondansetron is a serotonin (5-HT₃) receptor antagonist commonly used to treat nausea and vomiting from a variety of causes, including migraines, gastroenteritis, and postoperative states. It is effective at reducing emesis and improving tolerance of oral medications and fluids. Ondansetron can be administered orally, intravenously, or as an orally disintegrating tablet, making it useful when nausea limits swallowing. It is generally well tolerated, with headache and constipation being the most common side effects.

Treatment Type: Prescription Medication

Treatment Class: Seratonin antagonist

Treatment Modality: Injection, Intravenous (IV), Oral

Review Summary

5.0

1 Reviews

Preferred by 1 Reviewers

Based on the single review provided, Ondansetron appears to be highly effective in treating nausea, particularly during pregnancy. The reviewer rated the treatment 5 out of 5 and mentioned that it "works wonderfully." However, more reviews would be needed to draw a more comprehensive conclusion about the treatment's overall effectiveness.

This summary was generated by users' reviews

Breakdown by Category

Each categories are rated on a 1–5 scale, with 5 being the most favorable outcome and 1 being the least. These scores are averaged across all user reviews to provide a clear sense of how this treatment typically performs in each area.

Cost
5.0
1 = Very Expensive 5 = Very Affordable

5.0

Very Affordable
Relief Speed
5.0
1 = No Relief 5 = Immediate Relief

5.0

Immediate Relief
Side Effects
4.0
1 = Intolerable Effect 5 = No Effect

4.0

Mild Effect
Treatment Line
5.0
1 = Third-line or more 5 = First-line

5.0

First-line

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5.0

1 Reviews
5
100%
4
0%
3
0%
2
0%
1
0%

AI Summary of User Experiences

Not medical advice.

Based on the single review provided, Ondansetron appears to be highly effective in treating nausea, particularly during pregnancy. The reviewer rated the treatment 5 out of 5 and mentioned that it "works wonderfully." However, more reviews would be needed to draw a more comprehensive conclusion about the treatment's overall effectiveness.

Reviews

Filter by reviewer type Pro

Cost
Very Expensive
$1000+
Expensive
$501 to $1000
Moderate Cost
$101 to $500
Affordable
$25 to $100
Very Affordable
$25
Relief Speed
No Relief
No noticeable improvement
Slow Relief
Several days to weeks
Moderate Relief
Within 1 - 3 days
Fast Relief
Within hours
Immediate Relief
Within minutes
Side Effect
Intolerable Side Effect
Caused treatment to stop or required hospitalization
Severe Side Effect
Difficult to tolerate, may require intervention
Moderate Side Effect
Noticeable, but manageable
Mild Side Effect
Minor, not bothersome
No Side Effect
Without any adverse effects
Treatment Line
Third-line or more
Used after second-line failed or multiple prior treatment
Second-line
Used after first-line treatment failed or was unsuitable
First-line
First treatment tried
Dr. Curbside

Dr. Curbside

Verified
Physician • Emergency Medicine • How doctors think about decisions — and what real-world experiences add
3 months ago
Ondansetron is a first-line treatment for nausea and is especially useful when the underlying cause is unclear. It is highly effective and has one of the safest side effect profiles among antiemetic medications. Most patients tolerate it well, with constipation being one of the more commonly reported but generally mild side effects. Ondansetron is also available as an orally disintegrating tablet (ODT) that dissolves on the tongue, making it an excellent option for patients who are actively nauseated or unable to tolerate pills. Overall, it is a reliable and well-tolerated choice for acute nausea across a wide range of clinical settings.
#ReviewersPreferred #VeryAffordable #ImmediateRelief #MildEffect #First-line #Rescue/EmergencyUse