Other names: Nucala
Description:
Mepolizumab (Nucala) is a biologic medication injected used to treat severe eosinophilic asthma. It is a monoclonal antibody that targets interleukin-5 (IL-5), a key cytokine responsible for the growth and survival of eosinophils, which play a significant role in airway inflammation in eosinophilic asthma. Approved for patients ≥6 years old with severe eosinophilic asthma that is not well-controlled with standard inhalers (e.g., corticosteroids, long-acting beta-agonists).
Treatment For:
AI generated Summary: Based on the author's review, Mepolizumab is an effective add-on treatment for severe eosinophilic asthma when other treatments fail to control symptoms. It reduces exacerbations, improves lung function, and may decrease oral steroid dependence by targeting IL-5 to lower eosinophil-driven inflammation. The author rates the treatment's effectiveness as 3 out of 5.
Mepolizumab is an add-on treatment for severe eosinophilic asthma, used when high-dose inhaled corticosteroids and other controllers fail to control symptoms. It reduces exacerbations, improves lung function, and may decrease oral steroid dependence by targeting IL-5 to lower eosinophil-driven inflammation.
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