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Mepolizumab

Other names: Nucala

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Description:

Mepolizumab (Nucala) is a biologic medication injected used to treat severe eosinophilic asthma. It is a monoclonal antibody that targets interleukin-5 (IL-5), a key cytokine responsible for the growth and survival of eosinophils, which play a significant role in airway inflammation in eosinophilic asthma. Approved for patients ≥6 years old with severe eosinophilic asthma that is not well-controlled with standard inhalers (e.g., corticosteroids, long-acting beta-agonists).

Treatment For:

AI generated Summary: Based on the single expert review, Mepolizumab appears to be an effective add-on treatment for severe eosinophilic asthma when other standard therapies fail to control symptoms adequately. It works by targeting IL-5 to reduce eosinophil-driven inflammation, resulting in fewer exacerbations, improved lung function, and potentially decreased reliance on oral steroids.

Reviews

Average rating: 3/5
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Dr. Curbside

  • February 27, 2025

3.0

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