Categories: Prescription Medication
Description:
Magnesium sulfate is the standard of care for seizure prevention in moderate to severe preeclampsia and is also used to treat eclamptic seizures. It acts as a central nervous system depressant by blocking neuromuscular transmission and reducing cerebral irritability, thereby lowering the risk of seizures. It is administered intravenously with a loading dose followed by a continuous infusion. Because magnesium can accumulate and cause toxicity, regular monitoring is essential—including checking deep tendon reflexes, respiratory rate, and urine output. Loss of reflexes is often the earliest sign of toxicity and may require dose adjustment or discontinuation.
Treatment For:
AI generated Summary: Based on the review by Dr. Curbside, Magnesium Sulfate is considered the first-line treatment for preventing seizures in severe preeclampsia. It effectively reduces the risk of progression to eclampsia, but close monitoring is necessary to avoid toxicity, with deep tendon reflexes serving as an early indicator of potential side effects.
Magnesium sulfate is the first-line treatment for seizure prevention in severe preeclampsia. It significantly reduces the risk of progression to eclampsia and is closely monitored to avoid toxicity, with deep tendon reflexes serving as an early indicator.
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