Extended-release melatonin is an over-the-counter sleep aid used for insomnia, particularly difficulty staying asleep (sleep maintenance). It works by slowly releasing melatonin throughout the night, better mimicking the body’s natural overnight hormone pattern and helping maintain sleep.

Unlike immediate-release forms, it provides longer-lasting effects, which can reduce nighttime awakenings and improve overall sleep efficiency.

Best for: frequent awakenings or early morning waking
Less helpful for: falling asleep quickly

It is generally well tolerated, though some people may experience morning grogginess, vivid dreams, or headache.