Donanemab

Other names: Kisunla

Categories: Prescription Medication

Description:

Donanemab is a monoclonal antibody therapy being developed for patients with early Alzheimer’s disease. It works by clearing amyloid plaques from the brain and is given as a monthly intravenous infusion. Clinical trials suggest that it can slow memory loss and functional decline, with the strongest benefits seen in patients with lower to moderate levels of tau protein. The major risks include amyloid-related imaging abnormalities (ARIA) such as brain swelling or small bleeds, which require MRI monitoring. While not a cure, donanemab represents a promising disease-modifying option for early-stage Alzheimer’s.

Treatment For:

Alzheimer’s disease

AI generated Summary: Based on the provided information, there are no reviews or ratings available for the treatment 'Donanemab' against 'Alzheimer's disease'. As a result, it is not possible to determine the effectiveness of this treatment without further data or evidence.

Reviews

Average rating: 4/5

Physician ( 1 )

5

0
4

1
3

0
2

0
1

0

Average rating: 4.00/5

Total Reviews: 1

5

0
4

1
3

0
2

0
1

0

All Physician Healthcare provider (non-physician) Healthcare Consumer (Patients & Caregivers)

Dr. Curbside

September 30, 2025

4.0

Donanemab has demonstrated a ~30% slowing of cognitive and functional decline in patients with early Alzheimer’s disease, particularly those with low to medium tau pathology. Like other drugs in its class, it carries risks of amyloid-related imaging abnormalities (ARIA), including brain swelling and microhemorrhages, requiring regular MRI monitoring. Its use is best reserved for carefully selected patients with confirmed amyloid pathology, balancing modest clinical benefits against potential safety concerns.

Write a Review

Comments: *

Disclaimer

The information, including but not limited to, text, graphics, images and other material contained on this website/app are for informational purposes only. No material on this site/app is intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment and before undertaking a new health care regimen, and never disregard professional medical advice or delay in seeking it because of something you have read on this website/app.

Find the Best Treatments for Your Condition