Chlorpromazine

This is not medical advice. Always consult a licensed healthcare professional before starting or changing any treatment. Information here is based on personal experiences and may not apply to everyone.

Chlorpromazine (Thorazine) is the only FDA approved prescribed medication for persistent or intractable hiccups lasting over 48 hours. As a dopamine antagonist from the phenothiazine class, it works by affecting the brainstem, where the hiccup reflex is controlled. It blocks dopamine receptors, reducing involuntary diaphragm spasms, and has sedative effects that help relax muscles involved in hiccups. This makes it an effective treatment for severe or chronic cases when other remedies fail.

Treatment Type: Prescription Medication

Treatment Class: N/A

Treatment Modality: N/A

Review Summary

5.0

1 Reviews

Preferred by 1 Reviewers

Based on the single review provided, Chlorpromazine appears to be an effective treatment for intractable hiccups, as it is FDA approved for this condition. However, the reviewer cautions that one should be aware of the potential side effects associated with this medication.

This summary was generated by users' reviews

Breakdown by Category

Each categories are rated on a 1–5 scale, with 5 being the most favorable outcome and 1 being the least. These scores are averaged across all user reviews to provide a clear sense of how this treatment typically performs in each area.

Cost

5.0

1 = Very Expensive 5 = Very Affordable

5.0

Very Affordable

Relief Speed

5.0

1 = No Relief 5 = Immediate Relief

5.0

Immediate Relief

Side Effects

4.0

1 = Intolerable Effect 5 = No Effect

4.0

Mild Effect

Treatment Line

5.0

1 = Third-line or more 5 = First-line

5.0

First-line

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5.0

1 Reviews

100%

AI Summary of User Experiences

Not medical advice.

Reviews

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Cost

Very Expensive

$1000+

Expensive

$501 to $1000

Moderate Cost

$101 to $500

Affordable

$25 to $100

Very Affordable

$25

Relief Speed

No Relief

No noticeable improvement

Slow Relief

Several days to weeks

Moderate Relief

Within 1 - 3 days

Fast Relief

Within hours

Immediate Relief

Within minutes

Side Effect

Intolerable Side Effect

Caused treatment to stop or required hospitalization

Severe Side Effect

Difficult to tolerate, may require intervention

Moderate Side Effect

Noticeable, but manageable

Mild Side Effect

Minor, not bothersome

No Side Effect

Without any adverse effects

Treatment Line

Third-line or more

Used after second-line failed or multiple prior treatment

Second-line

Used after first-line treatment failed or was unsuitable

First-line

First treatment tried

Dr. Curbside

Verified

Physician • Emergency Medicine • How doctors think about decisions — and what real-world experiences add

1 month ago

Chlorpromazine is one of the more effective meds for stubborn hiccups and is actually the only FDA-approved option for this. It works well, but isn’t first-line because of side effects. Can cause drowsiness, dizziness, and low blood pressure, so it’s usually saved for more persistent cases when simple fixes don’t work.

#VeryAffordable #ImmediateRelief #MildEffect #First-line #Rescue/EmergencyUse

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