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Belimumab

Other names: Benlysta

Categories: Prescription Medication

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Description: Belimumab is a biologic therapy approved for the treatment of systemic lupus erythematosus (SLE) and lupus nephritis. It is a monoclonal antibody that targets BAFF (B-cell activating factor), reducing abnormal B-cell activity that drives lupus inflammation. Belimumab is a second-line treatment used when standard therapies (like corticosteroids, hydroxychloroquine, or immunosuppressants) are not sufficient to control disease. It is given IV or subcutaneously and is often added to background medications to help reduce flares and steroid use. It is generally well tolerated, but may increase the risk of infection and depression. Belimumab is particularly useful in patients with autoantibody-positive lupus and has also been approved for lupus nephritis in combination with other immunosuppressants.

Treatment For:

AI generated Summary: Based on the single review provided, Belimumab (Benlysta) appears to be an effective treatment for moderate to severe Systemic Lupus Erythematosus, particularly in autoantibody-positive patients. The reviewer, a doctor, rates the treatment 4 out of 5, noting that it helps reduce flares, lower steroid use, and is well-tolerated when administered via IV or subcutaneous injection.

Reviews

Average rating: 4/5
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Average rating: 4.00/5
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Dr. Curbside

  • June 8, 2025

4.0

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