Adapalene

Alternative Names: Differin, Differin XP

Adapalene 0.1% is a gentle retinoid (vitamin A-based medicine) that you put on your skin. It helps smooth out fine lines and improve skin texture by speeding up how your skin makes new cells. This helps get rid of old, damaged skin and brings in fresh, healthy skin.

Adapalene is less irritating than stronger retinoids like tretinoin, so it’s a good option for people with sensitive skin or those just starting out. You can buy adapalene 0.1% over the counter and is available in stronger doses with a prescription

It may take several weeks to see results, and it’s important to wear sunscreen because adapalene can make your skin more sensitive to the sun.

Treatment Type: Over the Counter Medication

Treatment Class: Retinoid

Treatment Modality: Topical

Review Summary

5.0

1 Reviews

Preferred by 1 Reviewers

Based on the single review provided, Adapalene 0.1% appears to be an effective over-the-counter treatment for fine lines and rough skin texture associated with wrinkles. The reviewer, Dr. Curbside, rates the treatment 5 out of 5, indicating that it is gentle enough for sensitive skin and can be used once daily at night after cleansing.

This summary was generated by users' reviews

Breakdown by Category

Each categories are rated on a 1–5 scale, with 5 being the most favorable outcome and 1 being the least. These scores are averaged across all user reviews to provide a clear sense of how this treatment typically performs in each area.

Cost
5.0
1 = Very Expensive 5 = Very Affordable

5.0

Very Affordable
Relief Speed
2.0
1 = No Relief 5 = Immediate Relief

2.0

Slow Relief
Side Effects
4.0
1 = Intolerable Effect 5 = No Effect

4.0

Mild Effect
Treatment Line
5.0
1 = Third-line or more 5 = First-line

5.0

First-line

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5.0

1 Reviews
5
100%
4
0%
3
0%
2
0%
1
0%

AI Summary of User Experiences

Not medical advice.

Based on the single review provided, Adapalene 0.1% appears to be an effective over-the-counter treatment for fine lines and rough skin texture associated with wrinkles. The reviewer, Dr. Curbside, rates the treatment 5 out of 5, indicating that it is gentle enough for sensitive skin and can be used once daily at night after cleansing.

Reviews

Filter by reviewer type Pro

Cost
Very Expensive
$1000+
Expensive
$501 to $1000
Moderate Cost
$101 to $500
Affordable
$25 to $100
Very Affordable
$25
Relief Speed
No Relief
No noticeable improvement
Slow Relief
Several days to weeks
Moderate Relief
Within 1 - 3 days
Fast Relief
Within hours
Immediate Relief
Within minutes
Side Effect
Intolerable Side Effect
Caused treatment to stop or required hospitalization
Severe Side Effect
Difficult to tolerate, may require intervention
Moderate Side Effect
Noticeable, but manageable
Mild Side Effect
Minor, not bothersome
No Side Effect
Without any adverse effects
Treatment Line
Third-line or more
Used after second-line failed or multiple prior treatment
Second-line
Used after first-line treatment failed or was unsuitable
First-line
First treatment tried
Dr. Curbside

Dr. Curbside

Verified
Physician • Emergency Medicine • How doctors think about decisions — and what real-world experiences add
2 months ago
Adapalene 0.1% is an over-the-counter (OTC) retinoid that’s a great starter option for improving fine lines and rough skin texture. It’s gentle enough for sensitive skin and can be used once daily at night after cleansing.
#VeryAffordable #SlowRelief #MildEffect #First-line #Maintenance #Preventative