Psoriasis is a chronic immune-mediated inflammatory skin disease characterized by well-demarcated, erythematous plaques with overlying silvery scale. It results from accelerated skin cell turnover driven by immune system activation, particularly involving inflammatory cytokines. Lesions most commonly affect the extensor surfaces, scalp, and lower back, and may be associated with itching, pain, or fissuring. Psoriasis is a systemic inflammatory condition and is associated with comorbidities such as psoriatic arthritis, cardiovascular disease, and metabolic syndrome.