Intralesional Candida antigen is an immunotherapy treatment where a small amount of Candida antigen is injected directly into a wart to stimulate the body’s immune system to recognize and clear HPV-infected tissue. Unlike destructive therapies (cryotherapy, salicylic acid), this approach can also trigger the immune system to clear distant untreated warts, making it helpful for multiple or stubborn lesions. Treatments are usually given every 3–4 weeks for several sessions until improvement or resolution occurs. Mild swelling, redness, or soreness at the injection site is common and indicates an active immune response. This is a useful option when standard treatments fail, and it avoids the blistering or scarring risks of more aggressive procedures.