Cryotherapy is an in-office treatment where liquid nitrogen is applied to freeze and destroy abnormal or unwanted skin tissue, commonly used for warts, actinic keratoses, and benign skin lesions. The extreme cold causes controlled tissue damage, allowing the area to blister, scab, and heal with healthy skin underneath. Treatment is quick and effective, though brief stinging, redness, blistering, or temporary skin color changes can occur. Some lesions may require more than one session. Over-the-counter freezing products are available but use weaker cooling agents and are less effective than medical liquid nitrogen. For persistent or thicker lesions, clinician-performed cryotherapy remains the preferred option.