Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) commonly used to help relieve sacroiliac (SI) joint pain caused by inflammation of the joint or surrounding ligaments. It works by blocking inflammatory chemicals in the body, which can reduce pain, swelling, and stiffness, especially during movement. People often take it for short-term relief while doing physical therapy or other treatments that address the underlying cause. It should be taken with food to reduce stomach upset, and individuals with kidney problems, ulcers, or blood-thinner use should discuss safety with a healthcare professional first.