Risperidone is an atypical antipsychotic that is FDA-approved for treating irritability in children and adolescents with autism spectrum disorder (ASD). It can help reduce severe symptoms such as aggression, self-injurious behavior, tantrums, and mood swings. While risperidone does not treat the core social and communication challenges of autism, it can improve overall functioning by reducing disruptive behaviors that interfere with learning and therapy.

Common side effects include weight gain, increased appetite, drowsiness, and hormonal changes (such as elevated prolactin), so regular monitoring is recommended.