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Average rating: 5/5
Physician ( 1 )
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Average rating: 5.00/5
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Memantine is a first-line drug for moderate to severe Alzheimer’s disease, often used alone or in combination with an acetylcholinesterase inhibitor. It works by blocking NMDA glutamate receptors, which helps reduce excitotoxicity and may protect brain cells. Clinical benefits are modest but include stabilization or slowing of decline in cognition, daily functioning, and behavioral symptoms, with generally good tolerability.
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