Lecanemab

Other names: Leqembi

Categories: Prescription Medication

Description:

Lecanemab is a monoclonal antibody treatment for early Alzheimer’s disease that targets beta-amyloid, helping clear plaques from the brain. It is given as an intravenous infusion every two weeks and has been shown to modestly slow cognitive and functional decline in clinical trials. The therapy is approved for use in patients with mild cognitive impairment or mild dementia due to Alzheimer’s. The most important risks include amyloid-related imaging abnormalities (ARIA), such as brain swelling or microbleeds, so patients require regular MRI monitoring. While not a cure, lecanemab is considered a disease-modifying therapy that offers a new option in early-stage treatment.

Treatment For:

Alzheimer’s disease

AI generated Summary: Based on the provided information, there are no reviews or ratings available for the treatment 'Lecanemab' against Alzheimer's disease. Without any user feedback or author review, it is not possible to determine the effectiveness of this treatment from the given data.

Reviews

Average rating: 4/5

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All Physician Healthcare provider (non-physician) Healthcare Consumer (Patients & Caregivers)

Dr. Curbside

September 30, 2025

4.0

Lecanemab has been shown to slow cognitive and functional decline by about 25–30% in early Alzheimer’s disease, offering meaningful though modest clinical benefit. However, treatment carries notable risks, including amyloid-related imaging abnormalities such as brain swelling and microhemorrhages, which require careful monitoring with MRI. Its use should be reserved for appropriately selected patients with confirmed amyloid pathology, weighing the potential benefits against safety concerns.

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