Benzathine Penicillin

Categories: Prescription Medication

Description:

Benzathine penicillin G is the gold standard treatment for syphilis. It is given as a long-acting intramuscular injection, which provides sustained drug levels to clear Treponema pallidum. A single 2.4 million unit dose is used for early syphilis, while later stages require weekly injections for three weeks. It is also the only proven treatment for preventing congenital syphilis in pregnancy. Side effects are uncommon but may include injection site pain or a temporary Jarisch–Herxheimer reaction after dosing.

Treatment For:

Syphilis

AI generated Summary: Based on the provided information, there are no reviews or ratings available for the treatment 'Benzathine Penicillin' against the disease 'Syphilis'. Without any user feedback or author review, it is not possible to determine the effectiveness of this treatment from the given data.

Reviews

Average rating: 5/5

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Average rating: 5.00/5

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All Physician Healthcare provider (non-physician) Healthcare Consumer (Patients & Caregivers)

Dr. Curbside

September 8, 2025

5.0

Benzathine penicillin G is the gold standard treatment for syphilis due to its proven effectiveness and ability to provide long-lasting blood levels that eradicate Treponema pallidum. For primary, secondary, or early latent syphilis, the recommended regimen is a single intramuscular injection of 2.4 million units. For late latent syphilis or syphilis of unknown duration, the regimen is 2.4 million units IM once weekly for three consecutive weeks. In neurosyphilis or ocular syphilis, intravenous aqueous penicillin is required instead. It is also the only therapy shown to reliably prevent congenital syphilis during pregnancy, making it essential in obstetric care.

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