Alirocumab

Other names: Praluent

Categories: Prescription Medication

Description:

Alirocumab (trade name Praluent) is a PCSK9 inhibitor used to treat elevated cholesterol, particularly in patients who need additional LDL lowering beyond statins or who cannot tolerate statins. It works by blocking the PCSK9 protein, which allows the liver to keep more LDL receptors on its surface, leading to greater clearance of LDL (“bad” cholesterol) from the bloodstream. Alirocumab is given as a subcutaneous injection every 2–4 weeks and can reduce LDL cholesterol by up to 60%. It is commonly prescribed for patients with familial hypercholesterolemia or established atherosclerotic cardiovascular disease to lower the risk of heart attack and stroke.

Treatment For:

Hypercholesterolemia

AI generated Summary: Based on the provided information, there are no user reviews available for the treatment 'Alirocumab' against 'Hypercholesterolemia'. The effectiveness of this treatment cannot be determined due to the lack of user feedback and ratings. More data is needed to assess the efficacy of Alirocumab in managing Hypercholesterolemia.

Reviews

Average rating: 3/5

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Average rating: 3.00/5

Total Reviews: 1

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All Physician Healthcare provider (non-physician) Healthcare Consumer (Patients & Caregivers)

Dr. Curbside

August 26, 2025

3.0

Alirocumab (Praluent) is a PCSK9 inhibitor that can lower LDL cholesterol by 50–60% and has proven benefit in reducing cardiovascular events. I consider it for patients with familial hypercholesterolemia or established ASCVD whose LDL remains above goal despite maximally tolerated statins and ezetimibe. Because it is costly and requires injections, I reserve it as a third-line option when aggressive cholesterol lowering is still needed.

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