Buspirone

Other names: BuSpar

Categories: Prescription Medication

Description:

Buspirone is an anti-anxiety medication primarily used for generalized anxiety disorder (GAD). Unlike benzodiazepines, it does not cause sedation, dependence, or withdrawal symptoms, making it a safer long-term option. It works by modulating serotonin and dopamine receptors but may take 2–4 weeks to show full effect. It's best for mild to moderate anxiety and is often used when patients cannot tolerate SSRIs or prefer a non-sedating option. Common side effects include dizziness, headache, and nausea.

Treatment For:

Anxiety

AI generated Summary: Based on the provided review, Buspirone is considered a second-line treatment for generalized anxiety disorder (GAD) and is typically used when patients cannot tolerate or do not respond well to first-line treatments like SSRIs or SNRIs. While it has a lower side effect burden and is non-sedating and non-addictive, its efficacy is generally more modest compared to first-line treatments.

Reviews

Average rating: 4/5

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All Physician Healthcare provider (non-physician) Healthcare Consumer (Patients & Caregivers)

Dr. Curbside

May 25, 2025

4.0

Buspirone is considered a second-line treatment for generalized anxiety disorder (GAD), typically used when patients cannot tolerate or do not respond well to SSRIs or SNRIs. It is non-sedating, non-addictive, and has a lower side effect burden, but its efficacy is generally more modest compared to first-line SSRIs like sertraline or escitalopram. It’s a good option for patients seeking an alternative to antidepressants or those concerned about sexual or cognitive side effects.

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