Lisinopril

Other names: Zestoretic, Zestril, Prinivil, and Qbrelis

Categories: Prescription Medication

Description:

Lisinopril is a commonly used first-line ACE inhibitor for hypertension. It works by blocking the renin-angiotensin-aldosterone system (RAAS), helping blood vessels relax and lowering blood pressure. ACE inhibitors like lisinopril are especially beneficial in patients with diabetes, chronic kidney disease, or heart failure, as they offer protective effects beyond just lowering blood pressure. However, they may cause cough or, rarely, angioedema, and should be avoided in pregnancy.

Treatment For:

Hypertension

AI generated Summary: Based on the single expert review provided, Lisinopril appears to be a highly effective first-line treatment for hypertension, particularly in patients with certain comorbidities such as diabetes, chronic kidney disease, or heart failure. The reviewer notes that Lisinopril not only lowers blood pressure but also offers protective benefits for the kidneys and heart, making it a valuable option for many patients, though it should be avoided in pregnancy and used cautiously in specific scenarios.

Reviews

Average rating: 5/5

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Average rating: 5.00/5

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All Physician Healthcare provider (non-physician) Healthcare Consumer (Patients & Caregivers)

Dr. Curbside

May 25, 2025

5.0

Lisinopril is used as a first-line treatment for hypertension, especially in patients with compelling indications such as diabetes, chronic kidney disease (CKD) with proteinuria, or heart failure with reduced ejection fraction (HFrEF). It’s also suitable for younger, non-Black patients without contraindications. Its benefits include not only lowering blood pressure but also protecting the kidneys and heart. However, it should be avoided in pregnancy and used cautiously in patients with bilateral renal artery stenosis or a history of angioedema.

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