Roflumilast

Alternative Names: Daliresp

Roflumilast (brand name Daliresp) is an oral phosphodiesterase-4 (PDE4) inhibitor used to reduce the risk of COPD exacerbations in patients with severe COPD and chronic bronchitis who have frequent flare-ups. It works by decreasing airway inflammation, complementing bronchodilator therapy. Roflumilast is not a bronchodilator itself and is typically used as an add-on to inhaled treatments like LABA or LAMA. Common side effects include weight loss, diarrhea, nausea, and insomnia, and it may not be well-tolerated by all patients. It’s best suited for patients with ongoing exacerbations despite optimized inhaler use.

Treatment Type: Prescription Medication

Treatment Class: Phosphodiesterase Inhibitors

Treatment Modality: Oral

Review Summary

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Based on the review, Roflumilast appears to be a specialized oral anti-inflammatory medication for severe COPD patients who experience frequent exacerbations despite standard inhaler treatments. While it can help reduce flare-ups, it comes with potential side effects like weight loss and gastrointestinal symptoms, making it suitable only for carefully selected patients who can tolerate the medication.

This summary was generated by users' reviews

Breakdown by Category

Each categories are rated on a 1–5 scale, with 5 being the most favorable outcome and 1 being the least. These scores are averaged across all user reviews to provide a clear sense of how this treatment typically performs in each area.

Cost
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1 = Very Expensive 5 = Very Affordable

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Very Expensive
Relief Speed
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1 = No Relief 5 = Immediate Relief

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No Relief
Side Effects
0
1 = Intolerable Effect 5 = No Effect

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Intolerable Effect
Treatment Line
0
1 = Third-line or more 5 = First-line

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Third-line or more

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AI Summary of User Experiences

Not medical advice.

Based on the review, Roflumilast appears to be a specialized oral anti-inflammatory medication for severe COPD patients who experience frequent exacerbations despite standard inhaler treatments. While it can help reduce flare-ups, it comes with potential side effects like weight loss and gastrointestinal symptoms, making it suitable only for carefully selected patients who can tolerate the medication.

Reviews

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Cost
Very Expensive
$1000+
Expensive
$501 to $1000
Moderate Cost
$101 to $500
Affordable
$25 to $100
Very Affordable
$25
Relief Speed
No Relief
No noticeable improvement
Slow Relief
Several days to weeks
Moderate Relief
Within 1 - 3 days
Fast Relief
Within hours
Immediate Relief
Within minutes
Side Effect
Intolerable Side Effect
Caused treatment to stop or required hospitalization
Severe Side Effect
Difficult to tolerate, may require intervention
Moderate Side Effect
Noticeable, but manageable
Mild Side Effect
Minor, not bothersome
No Side Effect
Without any adverse effects
Treatment Line
Third-line or more
Used after second-line failed or multiple prior treatment
Second-line
Used after first-line treatment failed or was unsuitable
First-line
First treatment tried

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