Metoclopramide

Other names: Reglan

Categories: Prescription Medication

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Description:

Reglan (metoclopramide) is a dopamine antagonist commonly used off-label for persistent or intractable hiccups. While primarily a gastroprokinetic agent that aids digestion and motility, it also affects the central nervous system, making it effective for hiccup treatment. It works by blocking dopamine receptors in the brainstem, which helps regulate the hiccup reflex arc. Additionally, it stimulates gastrointestinal motility, reducing irritation that may trigger hiccups, especially from GERD or gastric distension. Its antiemetic properties also make it useful for preventing nausea and vomiting.

Treatment For:

AI generated Summary: Based on the provided information, Metoclopramide (also known as Reglan) is widely used as an off-label treatment for hiccups, especially when gastrointestinal factors are involved. The author's rating of 4 out of 5 suggests that the treatment is considered effective for managing hiccups, although it is not officially indicated for this condition.

Reviews

Average rating: 4/5
Medical Physician ( 1 )
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Average rating: 4.00/5
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JAFERD+

  • March 6, 2025

4.0

While not officially indicated for hiccups, Reglan is widely used off-label for this condition, especially when gastrointestinal factors contribute.

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