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Metoclopramide

Other names: Reglan

Categories: Prescription Medication

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Description:

Reglan (metoclopramide) is a dopamine antagonist commonly used off-label for persistent or intractable hiccups. While primarily a gastroprokinetic agent that aids digestion and motility, it also affects the central nervous system, making it effective for hiccup treatment. It works by blocking dopamine receptors in the brainstem, which helps regulate the hiccup reflex arc. Additionally, it stimulates gastrointestinal motility, reducing irritation that may trigger hiccups, especially from GERD or gastric distension. Its antiemetic properties also make it useful for preventing nausea and vomiting.

Treatment For:

AI generated Summary: Based on the single review provided, Metoclopramide (Reglan) appears to be an effective treatment for hiccups, especially when gastrointestinal factors are involved, despite not being officially indicated for this condition. The reviewer, Dr. Curbside, rates the treatment as 4 out of 5, suggesting a high level of effectiveness when used off-label for hiccups.

Reviews

Average rating: 4/5
Physician ( 1 )
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Average rating: 4.00/5
Total Reviews: 1
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Dr. Curbside

  • March 6, 2025

4.0

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