Metoclopramide

Alternative Names: Reglan

Reglan (metoclopramide) is a dopamine antagonist commonly used off-label for persistent or intractable hiccups. While primarily a gastroprokinetic agent that aids digestion and motility, it also affects the central nervous system, making it effective for hiccup treatment. It works by blocking dopamine receptors in the brainstem, which helps regulate the hiccup reflex arc. Additionally, it stimulates gastrointestinal motility, reducing irritation that may trigger hiccups, especially from GERD or gastric distension. Its antiemetic properties also make it useful for preventing nausea and vomiting.

Treatment Type: Prescription Medication

Treatment Class: Dopamine agonist

Treatment Modality: Injection, Intravenous (IV), Other

Metoclopramide

Review Summary

4.0

1 Reviews

Preferred by 1 Reviewers

Based on the single review provided, Metoclopramide (Reglan) appears to be an effective treatment for hiccups, especially when gastrointestinal factors are involved, despite not being officially indicated for this condition. The reviewer, Dr. Curbside, rates the treatment as 4 out of 5, suggesting a high level of effectiveness when used off-label for hiccups.

This summary was generated by users' reviews

Breakdown by Category

Each categories are rated on a 1–5 scale, with 5 being the most favorable outcome and 1 being the least. These scores are averaged across all user reviews to provide a clear sense of how this treatment typically performs in each area.

Cost
5.0
1 = Very Expensive 5 = Very Affordable

5.0

Very Affordable
Relief Speed
4.0
1 = No Relief 5 = Immediate Relief

4.0

Fast Relief
Side Effects
4.0
1 = Intolerable Effect 5 = No Effect

4.0

Mild Effect
Treatment Line
3.0
1 = Third-line or more 5 = First-line

3.0

Second Line

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4.0

1 Reviews
5
0%
4
100%
3
0%
2
0%
1
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AI Summary of User Experiences

Not medical advice.

Based on the single review provided, Metoclopramide (Reglan) appears to be an effective treatment for hiccups, especially when gastrointestinal factors are involved, despite not being officially indicated for this condition. The reviewer, Dr. Curbside, rates the treatment as 4 out of 5, suggesting a high level of effectiveness when used off-label for hiccups.

Reviews

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Cost
Very Expensive
$1000+
Expensive
$501 to $1000
Moderate Cost
$101 to $500
Affordable
$25 to $100
Very Affordable
$25
Relief Speed
No Relief
No noticeable improvement
Slow Relief
Several days to weeks
Moderate Relief
Within 1 - 3 days
Fast Relief
Within hours
Immediate Relief
Within minutes
Side Effect
Intolerable Side Effect
Caused treatment to stop or required hospitalization
Severe Side Effect
Difficult to tolerate, may require intervention
Moderate Side Effect
Noticeable, but manageable
Mild Side Effect
Minor, not bothersome
No Side Effect
Without any adverse effects
Treatment Line
Third-line or more
Used after second-line failed or multiple prior treatment
Second-line
Used after first-line treatment failed or was unsuitable
First-line
First treatment tried
Dr. Curbside

Dr. Curbside

Verified
Physician • Emergency Medicine • How doctors think about decisions — and what real-world experiences add
1 month ago
An off-label option for persistent hiccups that can be effective by acting on the central hiccup reflex and improving gastric motility. It tends to work fairly quickly—often within hours to a day. Generally well tolerated short-term, but can cause drowsiness, restlessness, or extrapyramidal symptoms. A reasonable option when simple measures don’t work.
#VeryAffordable #FastRelief #MildEffect #Second-line #Rescue/EmergencyUse
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