Promethazine

This is not medical advice. Always consult a licensed healthcare professional before starting or changing any treatment. Information here is based on personal experiences and may not apply to everyone.

Alternative Names: Phenergan

Phenergan (promethazine) is an antihistamine with strong antiemetic properties commonly used to treat nausea and vomiting. It works primarily through H1 receptor blockade with additional anticholinergic and dopamine antagonist effects, making it effective for motion-related and medication-induced nausea. Phenergan can be given orally, rectally, intramuscularly, or intravenously, though IV use requires caution due to tissue injury risk. Common side effects include sedation, dizziness, and anticholinergic effects.

Treatment Type: Prescription Medication

Treatment Class: Anticholinergic

Treatment Modality: Genitorectal, Injection, Intravenous (IV), Oral

Review Summary

4.0

1 Reviews

Preferred by 1 Reviewers

Based on the single review provided, Promethazine appears to be an effective treatment for nausea, as the reviewer, Dr. Curbside, rated it 4 out of 5. However, the reviewer also mentioned that it is their second-line treatment due to its side effects, particularly extrapyramidal ones.

This summary was generated by users' reviews

Breakdown by Category

Each categories are rated on a 1–5 scale, with 5 being the most favorable outcome and 1 being the least. These scores are averaged across all user reviews to provide a clear sense of how this treatment typically performs in each area.

Cost

5.0

1 = Very Expensive 5 = Very Affordable

5.0

Very Affordable

Relief Speed

5.0

1 = No Relief 5 = Immediate Relief

5.0

Immediate Relief

Side Effects

3.0

1 = Intolerable Effect 5 = No Effect

3.0

Moderate Effect

Treatment Line

3.0

1 = Third-line or more 5 = First-line

3.0

Second Line

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4.0

1 Reviews

100%

AI Summary of User Experiences

Not medical advice.

Reviews

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Cost

Very Expensive

$1000+

Expensive

$501 to $1000

Moderate Cost

$101 to $500

Affordable

$25 to $100

Very Affordable

$25

Relief Speed

No Relief

No noticeable improvement

Slow Relief

Several days to weeks

Moderate Relief

Within 1 - 3 days

Fast Relief

Within hours

Immediate Relief

Within minutes

Side Effect

Intolerable Side Effect

Caused treatment to stop or required hospitalization

Severe Side Effect

Difficult to tolerate, may require intervention

Moderate Side Effect

Noticeable, but manageable

Mild Side Effect

Minor, not bothersome

No Side Effect

Without any adverse effects

Treatment Line

Third-line or more

Used after second-line failed or multiple prior treatment

Second-line

Used after first-line treatment failed or was unsuitable

First-line

First treatment tried

Dr. Curbside

Verified

Physician • Emergency Medicine • How doctors think about decisions — and what real-world experiences add

3 months ago

Works well, but a second line treatment for nausea, because of potential side effects, especially extra-pyramidal ones.

#VeryAffordable #ImmediateRelief #ModerateEffect #Second-line #Rescue/EmergencyUse #Preventative

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