The treatment landscape for sinusitis includes both symptomatic relief and targeted therapies. Pain, rhinorrhea, and fever are commonly managed with supportive care. Antibiotics like amoxicillin, amoxicillin-clavulanate, doxycycline, and levofloxacin are used to treat bacterial sinusitis, with the choice depending on factors such as severity, resistance patterns, and patient characteristics. Intranasal corticosteroids like fluticasone and decongestants such as pseudoephedrine and oxymetazoline provide symptomatic relief, while saline rinses help clear mucus and enhance the delivery of topical medications. The selection of treatment depends on the underlying cause, symptom severity, and individual patient factors.